"Abraham's Blossom" is a phrase referring both to a particular actress and to a sitcom series that never made it past the pilot episode.
Mayim Bialik is an actress—and neuroscientist!—known for various roles since the 1990s. Miyam is of Jewish descent and actually practices Judaism; considering her breakout role as the lead character in the sitcom
Blossom, it's no surprise that Bialik would sometimes be referred to as "Abraham's Blossom."
Rumor has it that prior to her work on
The Big Bang Theory, Bialik was in talks to star in a spinoff series, also titled
Abraham's Blossom. In the pilot, Bialik's former character has passed away, and her zany hijinks in the Jewish afterlife frustrate patriarchs like Abraham and Jacob. However, her heart of gold endears her to one and all—both the saved Jews kept in
Abraham's bosom and the tormented souls routinely begging her for water from the other side of death. Sadly, the series was not picked up by any networks, and no further episodes were made.